Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells

The eukaryotic translation initiation factor complex 4F (eIF4F) is the target of a potential chemotherapy in triple-negative breast cancer (TNBC). Organize complex is closed dependent translation initiation and consists of three core protein: eIF4E, eIF4G, and eIF4A1. In this study, we focus on the repositioning of the compound as a novel inhibitor-mediated translation eIF4A1.

In order to achieve this goal, a modified synthetic reporter assay was established. More specifically, a (CGG) 4 motif, which confers eIF4A dependence, incorporated into the 5′-leader of a luciferase-reporter tdTomato lentiviral constructs. The Prestwick Chemical Library then played in a couple of TNBC cell lines by measuring the intensity of fluorescent tdTomato.

We identified several potential inhibitors of cardiac glycosides as eIF4A1-mediated translation. Based on our study, we found that cardiac glycosides inhibit the expression of eIF4A1. To identify potential mechanism where this happens, we take advantage of Integrative Cell-Based Integrated Library Network Signatures (iLINCS). Our pursuit led us to the discovery that cardiac glycosides also reduce levels of c-MYC. Quantitative PCR confirms that the reduction in c-MYC and eIF4A happens at the level of transcription.

Thus, disruption eIF4A1 axis-c-MYC might be a viable approach in the treatment of TNBC. A novel combination rocaglamide and digoxin showed synergistic anti-cancer activity against TNBC cells in vitro. The findings in this study and others that are important to define the potential of combination chemotherapy on eIF4A1 in vivo. Thus, drug repositioning may be one of the classical approach to successfully targeting eIF4A1 in patients with TNBC.

Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells
Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells

Rbck1 ELISA Kit| Mouse RanBP-type and C3HC4-type zinc finger-co
EF016046 96 Tests
EUR 689

Dipeptidyl-Peptidase 4 Enzyme
abx073761-10ng 10 ng
EUR 328
  • Shipped within 5-10 working days.

Dipeptidyl-Peptidase 4 Enzyme
abx073761-2ng 2 ng
EUR 230
  • Shipped within 5-10 working days.

Dipeptidyl-Peptidase 4 Enzyme
abx073761-700ng 700 ng
EUR 6397
  • Shipped within 5-10 working days.

IL-4 Interleukin 4 Human Recombinant Protein, Yeast
PROTP05112-4 Regular: 10ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Co-1686
20-abx183952
  • EUR 356.00
  • EUR 523.00
  • 10 mg
  • 50 mg
  • Shipped within 1-2 weeks.

Co 102862
B7135-10 10 mg
EUR 276

Co 102862
B7135-50 50 mg
EUR 999

Individual Reaction Mix 4
G065-4 200 reactions
EUR 167

Human Lactate Dehydrogenase 4 Enzyme
abx070017-100Units 100 Units
EUR 1191
  • Shipped within 5-10 working days.

DNA Polymerase Enzyme (4 kb)
abx071004-10kU 10 kU
EUR 384
  • Shipped within 5-10 working days.

DNA Polymerase Enzyme (4 kb)
abx071004-3kU 3 kU
EUR 230
  • Shipped within 5-10 working days.

DNA Polymerase Enzyme (4 kb)
abx071004-500U 500 U
EUR 175
  • Shipped within 5-10 working days.

DNA Polymerase Enzyme (4 kb)
abx071004-50kU 50 kU
EUR 1052
  • Shipped within 5-10 working days.

Colorectal Cancer Exosome
P141-CO NULL
EUR 0

Colorectal Cancer Exosome RNA
P241-CO NULL
EUR 0

pBbA5c-MevT(CO)-T1-MBIS(CO, ispA)
PVT17450 2 ug
EUR 300

Frit Kit
FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

pLenti-CLDN1 shRNA-4 Plasmid
PVTBAV04867-4 2 ug
EUR 356

Feline IL-4 Recombinant Protein
R00230-4 5ug/vial
EUR 259
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

Column Packing Kit
PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

Recombinant Human Tumor Necrosis Factor Receptor Type 4
CC136-101 1mg
EUR 10310

PCR Mycoplasma Detection Kit
M034-Kit Kit
EUR 266

Recombinant Human sTNF Receptor Type II Protein
PROTP20333-4 20ug
EUR 317
Description: TNFRII is a member of the TNFR family of transmembrane proteins, and is expressed in immune cells and certain endothelial cells. It is a high affinity receptor for TNF-α but manifests a lower affinity to TNF-β. Signaling through this receptor regulates various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. Soluble TNFRII is capable of inhibiting TNF-α induced activities by acting as a decoy receptor. Recombinant human sTNFRII is an 18.9 kDa protein (174 amino acid residues) comprising the cysteine rich ligand binding portion of the extracellular domain of the TNFRII protein.

DIGITAL SHAKER FOR 4 MICROPLATES, 120V
6780-4 1/pk
EUR 798
Description: Lab Equipment; Shakers & Mixers

Mouse FibrOut 4, for brain, neural
4-20507 1 ml Ask for price

Mouse FibrOut 4, for brain, neural
4-20508 5 x 1 ml Ask for price

Rat FibrOut 4, for brain, neural
4-20533 1 ml Ask for price

Rat FibrOut 4, for brain, neural
4-20534 5 x 1 ml Ask for price

Human FibrOut 4, for brain, neural
4-21552 1 ml Ask for price

Human FibrOut 4, for brain, neural
4-21553 5 x 1 ml Ask for price

Recombinant Human 4-1BB Receptor Protein
PROTQ07011-4 20ug
EUR 317
Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.

Recombinant Human PF-4 (CXCL4) Protein
PROTP02776-4 20ug
EUR 317
Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

CO-1686 (Rociletinib)
2794-25
EUR 675

CO-1686 (Rociletinib)
2794-5
EUR 207

Co 101244 hydrochloride
B7062-10 10 mg
EUR 334

Co 101244 hydrochloride
B7062-50 50 mg
EUR 1243

Co-Precipitant, Pink
BIO-37075 1.5ml, 5mg/ml Ask for price

Lung Dissociation System 8 (Alveolar type II), Rat
4-20318 ea Ask for price

Bone Dissociation System 4 (Osteoblasts), Adult Mouse
4-20214 ea Ask for price

Liver Dissociation System 4 (Hepatocytes, rat), Rat
4-20304 ea Ask for price

Pituitary Dissociation System 4 (Pituitary), Adult mouse
4-20404 ea Ask for price

Thymus Dissociation System 4 (Epithelial), Adult rat
4-20444 ea Ask for price

StemBoost? Growth Factor Set V
K881-4
EUR 697

StemBoost? Growth Factor Set VII
K883-4
EUR 697

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS400A-KIT 1 kit (10 rxn)
EUR 1110
  • Category: Cas9

Human Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) ELISA Kit
abx387893-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV100PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV105PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV120PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV125PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-EU PLUG
6781-4 1/pk
EUR 798
Description: Lab Equipment; Shakers & Mixers

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-UK PLUG
6782-4 1/pk
EUR 798
Description: Lab Equipment; Shakers & Mixers

Cartilage Dissociation System 4 (Chondrocytes), Mouse and Rat
4-20234 ea Ask for price

Mammary Dissociation System 4 (Epithelial, Swiss 3T3), Mouse
4-20324 ea Ask for price

Pancreas Dissociation System 4 (Islets), Mouse and Rat
4-20374 ea Ask for price

Skin Dissociation System 4 (Keratinocytes), Mouse and Rat
4-20434 ea Ask for price

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS700A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS720A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS740A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Dengue virus type 4 PCR kit
PCR-H524-48R 50T
EUR 524.4
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Dengue virus type 4

Dengue virus type 4 PCR kit
PCR-H524-96R 100T
EUR 669.4
  • Contact us in order to know the reactivity of the kit.
Description: An conventional PCR kit for detection of Dengue virus type 4

Human Peroxisomal multifunctional enzyme type 2 (HSD17B4)
1-CSB-YP010774HU
  • EUR 430.00
  • EUR 234.00
  • EUR 1508.00
  • EUR 642.00
  • EUR 1009.00
  • EUR 291.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 81.7 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Peroxisomal multifunctional enzyme type 2(HSD17B4) expressed in Yeast

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
abx026859-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
abx026859-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx004727
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
abx216048-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx113089
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx121133
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx242132
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx242133
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx320221
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
abx234026-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx327690
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) Antibody
20-abx322147
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)
CAS510A-KIT 1 Kit
EUR 805
  • Category: Cas9

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
DLR-CA72-4-Hu-48T 48T
EUR 479
  • Should the Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 72-4 (CA72-4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
DLR-CA72-4-Hu-96T 96T
EUR 621
  • Should the Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 72-4 (CA72-4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
RDR-CA72-4-Hu-48Tests 48 Tests
EUR 500

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
RDR-CA72-4-Hu-96Tests 96 Tests
EUR 692

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
RD-CA72-4-Hu-48Tests 48 Tests
EUR 478

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit
RD-CA72-4-Hu-96Tests 96 Tests
EUR 662

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV200PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV205PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV220PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV225PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Drug screen-based high-speed image-clinical compounds against cell transmission adenovirus

Human adenovirus (HAdVs) which is fatal for immuno-suppressed individuals, but there is no effective therapy available anti-HAdV. Here, we present a high-throughput screening (HTS) of image-based platform-novel, which scores the full viral replication cycle of the virus into the spread of descent and the second round of infection.

We analyzed 1,280 small molecular weight compounds from Prestwick Chemical Library (PCL) for disturbances HAdV infection-C2 in quadruplicate, blind format, and perform powerful image analysis and a press screening. We present the entire set of data screening including all images, image analysis and data processing pipelines. The data is made available in Image Source Data (Rp, idr0081).

Our screen identified as an inhibitor Nelfinavir mesylate HAdV-C2 plaque formation of multi-round, but not a single round of infection. Nelfinavir was approved by the FDA for anti-retroviral therapy in humans. We underline the strength of the full cycle of infection tests in identifying inhibitors of image-based viruses with clinical potential.

A new coronavirus, called SARS-CoV-2, appeared in 2019 in China and quickly spread around the world. Since there are no approved therapies exist to treat COVID 19th, diseases associated with SARS-Cov-2, there is an urgent need to propose a molecule that can quickly get into the clinic. Approved drug repurposing is a strategy that can bypass time-consuming phase of drug development. In this study, we screened Prestwick Chemical Library consists of 1,520 drugs approved in the infected cell-based assay.

 

Ethanol Colorimetric/Fluorometric Assay Kit
K620-100
EUR 561

Ethanol Colorimetric/Fluorometric Assay Kit
K2125-100 100 assays
EUR 586

Enzyme Alpha-Amylase Assay Kit
Z5030046 100 assays
EUR 930
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Citrate Synthase Enzyme Assay
CSE1 1 Kit
EUR 349

Ethanol, anhydrous (85%)
D0193 500ml
EUR 60.55
  • Product category: Biochemicals/Solvents

Nonylphenoxypoly(Ethyleneoxy)Ethanol
abx188824-1kg 1 kg
EUR 244
  • Shipped within 1-2 weeks.

2-(cyclohexylamino)ethanol
20-abx181617
  • EUR 384.00
  • EUR 244.00
  • EUR 940.00
  • 100 g
  • 25 g
  • 500 g
  • Shipped within 1-2 weeks.

Ethanol, Absolute , 99.5%
E8510-001 1L Ask for price

Ethanol, Absolute , 99.5%
E8510-101 1 GAL Ask for price

Ethanol, Absolute , 99.5%
E8510-105 5 GAL Ask for price

Endothelin Converting Enzyme 1 Activity Assay Kit (Fluorometric)
K536-100
EUR 533

Nitric Oxide Synthase (NOS) enzyme assay, colorimetric micro assay kit, 96 test, Quantitative
1290-NOS-1 1 kit
EUR 651

Angiotensin II Converting Enzyme (ACE2) Activity Assay Kit (Fluorometric)
K897-100
EUR 512

Angiotensin I Converting Enzyme Activity (ACE1) Assay Kit (Fluorometric)
K227-100
EUR 572

Human Phosphatidyl ethanol（Peth）ELISA Kit
QY-E05459 96T
EUR 361

2-(2-azidoethoxy)ethanol
20-abx186161
  • EUR 411.00
  • EUR 787.00
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

6-Methylpyridine-2-ethanol
20-abx182315
  • EUR 1762.00
  • EUR 509.00
  • EUR 1288.00
  • 10 g
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(2,4-Dinitrophenoxy)Ethanol
20-abx182919
  • EUR 857.00
  • EUR 286.00
  • EUR 565.00
  • 10 g
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(2-Chloroethoxy)ethanol
20-abx182920
  • EUR 217.00
  • EUR 189.00
  • EUR 175.00
  • 100 g
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(4-Hydroxyphenyl)ethanol
GK8928-100G 100 g
EUR 134

2-(4-Hydroxyphenyl)ethanol
GK8928-25G 25 g
EUR 79

2-(4-Hydroxyphenyl)ethanol
GK8928-5G 5 g
EUR 53

Encephalitozoon cuniculi ELISA Enzyme Linked Immuno Sorbent Assay
18-9001-1 1 kit
EUR 565

Frit Kit
FRIT-KIT 1each
EUR 124
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor)ELISA kit
MEA462Ge-10x96wellstestplate 10x96-wells test plate
EUR 4954.03
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assa
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) in serum, plasma, urine and other biological fluids.

Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor)ELISA kit
MEA462Ge-1x48wellstestplate 1x48-wells test plate
EUR 495.63
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assa
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) in serum, plasma, urine and other biological fluids.

Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor)ELISA kit
MEA462Ge-1x96wellstestplate 1x96-wells test plate
EUR 665.18
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assa
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) in serum, plasma, urine and other biological fluids.

Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor)ELISA kit
MEA462Ge-5x96wellstestplate 5x96-wells test plate
EUR 2693.31
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assa
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) in serum, plasma, urine and other biological fluids.

Column Packing Kit
PACK-KIT 1pack
EUR 1035
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit
M034-Kit Kit
EUR 266

2-(2-Amino-4-nitroanilino)ethanol
20-abx180202
  • EUR 634.00
  • EUR 314.00
  • EUR 217.00
  • 100 g
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(N-Ethyl-m-toluidino)ethanol
20-abx180214
  • EUR 272.00
  • EUR 217.00
  • EUR 411.00
  • 100 g
  • 25 g
  • 500 g
  • Shipped within 1-2 weeks.

N-Boc-Aminoehtoxy-Ethoxy-Ethoxy-Ethanol
20-abx180839
  • EUR 411.00
  • EUR 523.00
  • 0.5 g
  • 1 g
  • Shipped within 1-2 weeks.

2-(9H-Carbazol-9-yl)ethanol
20-abx181609
  • EUR 676.00
  • EUR 258.00
  • EUR 453.00
  • 10 g
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(4-Amino-2-nitroanilino)-ethanol
20-abx184974
  • EUR 551.00
  • EUR 272.00
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

2-[2-(2-Chloroethoxy)Ethoxy]Ethanol
20-abx185012
  • EUR 258.00
  • EUR 509.00
  • 100 g
  • 500 g
  • Shipped within 1-2 weeks.

2-[2-(2-Aminoethoxy)Ethoxy]Ethanol
abx186612-1g 1 g
EUR 300
  • Shipped within 1-2 weeks.

2-[2-(2-Azidoethoxy)Ethoxy]Ethanol
20-abx187846
  • EUR 328.00
  • EUR 328.00
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

Z-His(Z)-OH ethanol solvate
C-2915.0025 25.0g
EUR 187
Description: Sum Formula: C22H21N3O6

Z-His(Z)-OH ethanol solvate
C-2915.0100 100.0g
EUR 490
Description: Sum Formula: C22H21N3O6

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS400A-KIT 1 kit (10 rxn)
EUR 1110
  • Category: Cas9

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV100PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV105PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV120PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV125PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS700A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS720A-KIT 10 rxn
EUR 1132
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS740A-KIT 10 rxn
EUR 1132
  • Category: Cas9

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)
CAS510A-KIT 1 Kit
EUR 805
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV200PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV205PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV220PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV225PA-KIT 1 Kit
EUR 1132
  • Category: Cas9

Glycosaminoglycans Assay Kit
6022 1 kit
EUR 419.75
Description: Glycosaminoglycans Assay Kit

DNA Assay Kit
6023 1 kit
EUR 180.5
Description: DNA Assay Kit

Hemoglobin Assay Kit
6024 1 kit
EUR 180.5
Description: Hemoglobin Assay Kit

Proteasome Assay Kit
55R-1341 100 assays
EUR 654
Description: Assay Kit for detection of Proteasome in the research laboratory

Calpain Assay Kit
55R-1342 100 assays
EUR 779
Description: Assay Kit for detection of Calpain in the research laboratory

Glutathione Assay Kit
55R-1343 100 assays
EUR 654
Description: Assay Kit for detection of Glutathione in the research laboratory

Glutathione Assay Kit
55R-1354 100 assays
EUR 895
Description: Assay Kit for detection of Glutathione activity in the research laboratory

HDAC Assay Kit
55R-1371 100 assays
EUR 673
Description: Assay Kit for detection of HDAC in the research laboratory

HDAC Assay Kit
55R-1372 100 assays
EUR 673
Description: Assay Kit for detection of HDAC in the research laboratory

HAT Assay Kit
55R-1373 100 assays
EUR 740
Description: Assay Kit for detection of HAT in the research laboratory

SOD Assay Kit
55R-1374 100 assays
EUR 602
Description: Assay Kit for detection of SOD in the research laboratory

HDAC3 Assay Kit
55R-1377 100 assays
EUR 693
Description: Assay Kit for detection of HDAC3 in the research laboratory

HDAC8 Assay Kit
55R-1379 100 assays
EUR 689
Description: Assay Kit for detection of HDAC8 in the research laboratory

ATP Assay Kit
55R-1380 100 assays
EUR 809
Description: Assay Kit for detection of ATP in the research laboratory

ADP Assay Kit
55R-1381 100 assays
EUR 809
Description: Assay Kit for detection of ADP in the research laboratory

FAD Assay Kit
55R-1382 100 assays
EUR 732
Description: Assay Kit for detection of FAD in the research laboratory

PEP Assay Kit
55R-1384 100 assays
EUR 876
Description: Assay Kit for detection of PEP in the research laboratory

Ammonia Assay Kit
55R-1388 100 assays
EUR 740
Description: Assay Kit for detection of Ammonia in the research laboratory

cAMP Assay Kit
55R-1389 100 assays
EUR 706
Description: Assay Kit for detection of cAMP activity in the research laboratory

cGMP Assay Kit
55R-1390 100 assays
EUR 706
Description: Assay Kit for detection of cGMP activity in the research laboratory

Urea Assay Kit
55R-1391 100 assays
EUR 740
Description: Assay Kit for detection of Urea in the research laboratory

Calcium Assay Kit
55R-1392 250 assays
EUR 586
Description: Assay Kit for detection of Calcium activity in the research laboratory

Magnesium Assay Kit
55R-1393 100 assays
EUR 654
Description: Assay Kit for detection of Magnesium in the research laboratory

Zinc Assay Kit
55R-1394 100 assays
EUR 673
Description: Assay Kit for detection of Zinc in the research laboratory

Iron Assay Kit
55R-1395 100 assays
EUR 758
Description: Assay Kit for detection of Iron in the research laboratory

Phosphate Assay Kit
55R-1400 500 assays
EUR 415
Description: Assay Kit for detection of Phosphate in the research laboratory

JNK Assay Kit
55R-1407 40 assays
EUR 868
Description: Assay Kit for detection of JNK in the research laboratory

JNK Assay Kit
55R-1408 40 assays
EUR 979
Description: Assay Kit for detection of JNK in the research laboratory

Akt Assay Kit
55R-1409 40 assays
EUR 979
Description: Assay Kit for detection of Akt in the research laboratory

Ammonia Assay Kit
55R-1410 100 assays
EUR 740
Description: Assay Kit for detection of Ammonia in the research laboratory

Cobalt Assay Kit
55R-1435 100 assays
EUR 621
Description: Assay Kit for detection of Cobalt in the research laboratory

Nickel Assay Kit
55R-1436 100 assays
EUR 621
Description: Assay Kit for detection of Nickel in the research laboratory

Chloride Assay Kit
55R-1437 100 assays
EUR 484
Description: Assay Kit for detection of Chloride in the research laboratory

Aspartate Assay Kit
55R-1438 100 assays
EUR 673
Description: Assay Kit for detection of Aspartate in the research laboratory

Hydroxyproline Assay Kit
55R-1439 100 assays
EUR 844
Description: Assay Kit for detection of Hydroxyproline in the research laboratory

Phenylalanine Assay Kit
55R-1442 100 assays
EUR 654
Description: Assay Kit for detection of Phenylalanine in the research laboratory