Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells

The eukaryotic translation initiation factor complex 4F (eIF4F) is the target of a potential chemotherapy in triple-negative breast cancer (TNBC). Organize complex is closed dependent translation initiation and consists of three core protein: eIF4E, eIF4G, and eIF4A1. In this study, we focus on the repositioning of the compound as a novel inhibitor-mediated translation eIF4A1.

In order to achieve this goal, a modified synthetic reporter assay was established. More specifically, a (CGG) 4 motif, which confers eIF4A dependence, incorporated into the 5′-leader of a luciferase-reporter tdTomato lentiviral constructs. The Prestwick Chemical Library then played in a couple of TNBC cell lines by measuring the intensity of fluorescent tdTomato.

We identified several potential inhibitors of cardiac glycosides as eIF4A1-mediated translation. Based on our study, we found that cardiac glycosides inhibit the expression of eIF4A1. To identify potential mechanism where this happens, we take advantage of Integrative Cell-Based Integrated Library Network Signatures (iLINCS). Our pursuit led us to the discovery that cardiac glycosides also reduce levels of c-MYC. Quantitative PCR confirms that the reduction in c-MYC and eIF4A happens at the level of transcription.

Thus, disruption eIF4A1 axis-c-MYC might be a viable approach in the treatment of TNBC. A novel combination rocaglamide and digoxin showed synergistic anti-cancer activity against TNBC cells in vitro. The findings in this study and others that are important to define the potential of combination chemotherapy on eIF4A1 in vivo. Thus, drug repositioning may be one of the classical approach to successfully targeting eIF4A1 in patients with TNBC.

 Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells
Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1-Mediated Translation in Triple-Negative Breast Cancer Cells

Dipeptidyl-Peptidase 4 Enzyme

abx073761-10ng 10 ng
EUR 328.00
  • Shipped within 5-10 working days.

Dipeptidyl-Peptidase 4 Enzyme

abx073761-2ng 2 ng
EUR 230.00
  • Shipped within 5-10 working days.

Dipeptidyl-Peptidase 4 Enzyme

abx073761-700ng 700 ng
EUR 6397.00
  • Shipped within 5-10 working days.

IL-4 Interleukin 4 Human Recombinant Protein, Yeast

PROTP05112-4 Regular: 10ug
EUR 317.00
Description: Interleukin-4 Human Recombinant produced in yeast is a single, glycosylated polypeptide chain containing 129 amino acids.;The IL-4 is purified by proprietary chromatographic techniques.

Rbck1 ELISA Kit| Mouse RanBP-type and C3HC4-type zinc finger-co

EF016046 96 Tests
EUR 689.00

Colorectal Cancer Exosome RNA

P241-CO NULL
EUR NULL

Colorectal Cancer Exosome

P141-CO NULL
EUR NULL

Individual Reaction Mix 4

G065-4 200 reactions
EUR 167.00

Co-1686

20-abx183952
  • EUR 356.00
  • EUR 523.00
  • 10 mg
  • 50 mg
  • Shipped within 1-2 weeks.

Co 102862

B7135-10 10 mg
EUR 276.00

Co 102862

B7135-50 50 mg
EUR 999.00

Frit Kit

FRIT-KIT 1each
EUR 124.00
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Human Lactate Dehydrogenase 4 Enzyme

abx070017-100Units 100 Units
EUR 1191.00
  • Shipped within 5-10 working days.

DNA Polymerase Enzyme (4 kb)

abx071004-10kU 10 kU
EUR 384.00
  • Shipped within 5-10 working days.

DNA Polymerase Enzyme (4 kb)

abx071004-3kU 3 kU
EUR 230.00
  • Shipped within 5-10 working days.

DNA Polymerase Enzyme (4 kb)

abx071004-500U 500 U
EUR 175.00
  • Shipped within 5-10 working days.

DNA Polymerase Enzyme (4 kb)

abx071004-50kU 50 kU
EUR 1052.00
  • Shipped within 5-10 working days.

pLenti-CLDN1 shRNA-4 Plasmid

PVTBAV04867-4 2 ug
EUR 356.00

Feline IL-4 Recombinant Protein

R00230-4 5ug/vial
EUR 259.00
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Feline IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

Column Packing Kit

PACK-KIT 1pack
EUR 1035.00
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

pBbA5c-MevT(CO)-T1-MBIS(CO, ispA)

PVT17450 2 ug
EUR 300.00

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266.00

Mouse FibrOut 4, for brain, neural

4-20507 1 ml Ask for price

Mouse FibrOut 4, for brain, neural

4-20508 5 x 1 ml Ask for price

Rat FibrOut 4, for brain, neural

4-20533 1 ml Ask for price

Rat FibrOut 4, for brain, neural

4-20534 5 x 1 ml Ask for price

Human FibrOut 4, for brain, neural

4-21552 1 ml Ask for price

Human FibrOut 4, for brain, neural

4-21553 5 x 1 ml Ask for price

DIGITAL SHAKER FOR 4 MICROPLATES, 120V

6780-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

Recombinant Human 4-1BB Receptor Protein

PROTQ07011-4 20ug
EUR 317.00
Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.

Recombinant Human PF-4 (CXCL4) Protein

PROTP02776-4 20ug
EUR 317.00
Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Recombinant Human sTNF Receptor Type II Protein

PROTP20333-4 20ug
EUR 317.00
Description: TNFRII is a member of the TNFR family of transmembrane proteins, and is expressed in immune cells and certain endothelial cells. It is a high affinity receptor for TNF-α but manifests a lower affinity to TNF-β. Signaling through this receptor regulates various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. Soluble TNFRII is capable of inhibiting TNF-α induced activities by acting as a decoy receptor. Recombinant human sTNFRII is an 18.9 kDa protein (174 amino acid residues) comprising the cysteine rich ligand binding portion of the extracellular domain of the TNFRII protein.

Recombinant Human Tumor Necrosis Factor Receptor Type 4

CC136-101 1mg
EUR 10310.00

Bone Dissociation System 4 (Osteoblasts), Adult Mouse

4-20214 ea Ask for price

Liver Dissociation System 4 (Hepatocytes, rat), Rat

4-20304 ea Ask for price

Pituitary Dissociation System 4 (Pituitary), Adult mouse

4-20404 ea Ask for price

Thymus Dissociation System 4 (Epithelial), Adult rat

4-20444 ea Ask for price

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110.00
  • Category: Cas9

Lung Dissociation System 8 (Alveolar type II), Rat

4-20318 ea Ask for price

StemBoost? Growth Factor Set V

K881-4
EUR 697.00

StemBoost? Growth Factor Set VII

K883-4
EUR 697.00

Co 101244 hydrochloride

B7062-10 10 mg
EUR 334.00

Co 101244 hydrochloride

B7062-50 50 mg
EUR 1243.00

Co-Precipitant, Pink

BIO-37075 1.5ml, 5mg/ml Ask for price

CO-1686 (Rociletinib)

2794-25
EUR 675.00

CO-1686 (Rociletinib)

2794-5
EUR 207.00

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Cartilage Dissociation System 4 (Chondrocytes), Mouse and Rat

4-20234 ea Ask for price

Mammary Dissociation System 4 (Epithelial, Swiss 3T3), Mouse

4-20324 ea Ask for price

Pancreas Dissociation System 4 (Islets), Mouse and Rat

4-20374 ea Ask for price

Skin Dissociation System 4 (Keratinocytes), Mouse and Rat

4-20434 ea Ask for price

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-EU PLUG

6781-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

DIGITAL SHAKER FOR 4 MICROPLATES, 230V-UK PLUG

6782-4 1/pk
EUR 798.00
Description: Lab Equipment; Shakers & Mixers

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 805.00
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

AXYGEN® AXYPET® PRO STARTER KIT: 4 PIPETTORS, PLEXI STAND, SAMPLE TIPS

AP-STR-KIT-P 1/pk
EUR 721.00
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 153.00
  • Category: Cas9

Adipose/Fat Dissociation System 4 (Predipocytes), Mouse and Rat

4-20194 ea Ask for price

Brain Dissociation System 4 (Endothelial, Microvessels), Mouse and Rat

4-20224 ea Ask for price

Endothelial Dissociation System 4 (Endothelial,Cerebral), Mouse and Rat

4-20244 ea Ask for price

Heart Dissociation System 4 (Myocytes,Ventricles), Mouse and Rat

4-20274 ea Ask for price

Muscle Dissociation System 4 (Smooth muscle), Mouse and Rat

4-20334 ea Ask for price

Parotid Dissociation System 4 (Parotid acinar), Mouse and Rat

4-20394 ea Ask for price

Lung Dissociation System 8 (Alveolar type I), Mouse and Rat

4-20315 ea Ask for price

Lung Dissociation System 6 (Fibroblasts & Type II), Mouse and Rat

4-20316 ea Ask for price

Lung Dissociation System 7 (Alveolar type II, Alveolar epithelial), Mouse

4-20317 ea Ask for price

Human Peroxisomal Multifunctional Enzyme Type 2 (HSD17B4) ELISA Kit

abx387893-96tests 96 tests
EUR 911.00
  • Shipped within 5-12 working days.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DL-CA72-4-Hu-192 1 kit of 192 tests
EUR 1054.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human Carbohydrate Antigen 72-4 (CA72-4)

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DL-CA72-4-Hu-48 1 kit of 48 tests
EUR 447.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human Carbohydrate Antigen 72-4 (CA72-4)

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DL-CA72-4-Hu-96 1 kit of 96 tests
EUR 597.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human Carbohydrate Antigen 72-4 (CA72-4)

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DLR-CA72-4-Hu-48T 48T
EUR 479.00
  • Should the Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 72-4 (CA72-4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

DLR-CA72-4-Hu-96T 96T
EUR 621.00
  • Should the Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Carbohydrate Antigen 72-4 (CA72-4) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

RDR-CA72-4-Hu-48Tests 48 Tests
EUR 500.00

Human Carbohydrate Antigen 72-4 (CA72-4) ELISA Kit

RDR-CA72-4-Hu-96Tests 96 Tests
EUR 692.00

Drug screen-based high-speed image-clinical compounds against cell transmission adenovirus

Human adenovirus (HAdVs) which is fatal for immuno-suppressed individuals, but there is no effective therapy available anti-HAdV. Here, we present a high-throughput screening (HTS) of image-based platform-novel, which scores the full viral replication cycle of the virus into the spread of descent and the second round of infection.

We analyzed 1,280 small molecular weight compounds from Prestwick Chemical Library (PCL) for disturbances HAdV infection-C2 in quadruplicate, blind format, and perform powerful image analysis and a press screening. We present the entire set of data screening including all images, image analysis and data processing pipelines. The data is made available in Image Source Data (Rp, idr0081).

Our screen identified as an inhibitor Nelfinavir mesylate HAdV-C2 plaque formation of multi-round, but not a single round of infection. Nelfinavir was approved by the FDA for anti-retroviral therapy in humans. We underline the strength of the full cycle of infection tests in identifying inhibitors of image-based viruses with clinical potential.

A new coronavirus, called SARS-CoV-2, appeared in 2019 in China and quickly spread around the world. Since there are no approved therapies exist to treat COVID 19th, diseases associated with SARS-Cov-2, there is an urgent need to propose a molecule that can quickly get into the clinic. Approved drug repurposing is a strategy that can bypass time-consuming phase of drug development. In this study, we screened Prestwick Chemical Library consists of 1,520 drugs approved in the infected cell-based assay.

 

Ethanol Colorimetric/Fluorometric Assay Kit

K2125-100 100 assays
EUR 586.00

Ethanol Colorimetric/Fluorometric Assay Kit

K620-100
EUR 561.00

Enzyme Alpha-Amylase Assay Kit

Z5030046 100 assays
EUR 930.00
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Citrate Synthase Enzyme Assay

CSE1 1 Kit
EUR 349.00

2-(cyclohexylamino)ethanol

20-abx181617
  • EUR 384.00
  • EUR 244.00
  • EUR 940.00
  • 100 g
  • 25 g
  • 500 g
  • Shipped within 1-2 weeks.

Nonylphenoxypoly(Ethyleneoxy)Ethanol

abx188824-1kg 1 kg
EUR 244.00
  • Shipped within 1-2 weeks.

Ethanol, anhydrous (85%)

D0193 500ml
EUR 60.55
  • Product category: Biochemicals/Solvents

Ethanol, Absolute , 99.5%

E8510-001 1L Ask for price

Ethanol, Absolute , 99.5%

E8510-101 1 GAL Ask for price

Ethanol, Absolute , 99.5%

E8510-105 5 GAL Ask for price

Endothelin Converting Enzyme 1 Activity Assay Kit (Fluorometric)

K536-100
EUR 533.00

Nitric Oxide Synthase (NOS) enzyme assay, colorimetric micro assay kit, 96 test, Quantitative

1290-NOS-1 1 kit
EUR 651.00

Angiotensin I Converting Enzyme Activity (ACE1) Assay Kit (Fluorometric)

K227-100
EUR 572.00

Angiotensin II Converting Enzyme (ACE2) Activity Assay Kit (Fluorometric)

K897-100
EUR 512.00

6-Methylpyridine-2-ethanol

20-abx182315
  • EUR 1762.00
  • EUR 509.00
  • EUR 1288.00
  • 10 g
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(2,4-Dinitrophenoxy)Ethanol

20-abx182919
  • EUR 857.00
  • EUR 286.00
  • EUR 565.00
  • 10 g
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(2-Chloroethoxy)ethanol

20-abx182920
  • EUR 217.00
  • EUR 189.00
  • EUR 175.00
  • 100 g
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(2-azidoethoxy)ethanol

20-abx186161
  • EUR 411.00
  • EUR 787.00
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(4-Hydroxyphenyl)ethanol

GK8928-100G 100 g
EUR 134.00

2-(4-Hydroxyphenyl)ethanol

GK8928-25G 25 g
EUR 79.00

2-(4-Hydroxyphenyl)ethanol

GK8928-5G 5 g
EUR 53.00

Human Phosphatidyl ethanol(Peth)ELISA Kit

QY-E05459 96T
EUR 361.00

Encephalitozoon cuniculi ELISA Enzyme Linked Immuno Sorbent Assay

18-9001-1 1 kit
EUR 565.00

Frit Kit

FRIT-KIT 1each
EUR 124.00
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Column Packing Kit

PACK-KIT 1pack
EUR 1035.00
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 266.00

Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor)ELISA kit

MEA462Ge-10x96wellstestplate 10x96-wells test plate
EUR 4954.03
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assa
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) in serum, plasma, urine and other biological fluids.

Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor)ELISA kit

MEA462Ge-1x48wellstestplate 1x48-wells test plate
EUR 495.63
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assa
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) in serum, plasma, urine and other biological fluids.

Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor)ELISA kit

MEA462Ge-1x96wellstestplate 1x96-wells test plate
EUR 665.18
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assa
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) in serum, plasma, urine and other biological fluids.

Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor)ELISA kit

MEA462Ge-5x96wellstestplate 5x96-wells test plate
EUR 2693.31
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assa
  • Show more
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mini Samples Enzyme-linked Immunosorbent Assay For Cortisol (Cor) in serum, plasma, urine and other biological fluids.

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1110.00
  • Category: Cas9

2-(9H-Carbazol-9-yl)ethanol

20-abx181609
  • EUR 676.00
  • EUR 258.00
  • EUR 453.00
  • 10 g
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

Z-His(Z)-OH ethanol solvate

C-2915.0025 25.0g
EUR 187.00
Description: Sum Formula: C22H21N3O6

Z-His(Z)-OH ethanol solvate

C-2915.0100 100.0g
EUR 490.00
Description: Sum Formula: C22H21N3O6

2-(2-Amino-4-nitroanilino)ethanol

20-abx180202
  • EUR 634.00
  • EUR 314.00
  • EUR 217.00
  • 100 g
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

2-(N-Ethyl-m-toluidino)ethanol

20-abx180214
  • EUR 272.00
  • EUR 217.00
  • EUR 411.00
  • 100 g
  • 25 g
  • 500 g
  • Shipped within 1-2 weeks.

N-Boc-Aminoehtoxy-Ethoxy-Ethoxy-Ethanol

20-abx180839
  • EUR 411.00
  • EUR 523.00
  • 0.5 g
  • 1 g
  • Shipped within 1-2 weeks.

2-(4-Amino-2-nitroanilino)-ethanol

20-abx184974
  • EUR 551.00
  • EUR 272.00
  • 25 g
  • 5 g
  • Shipped within 1-2 weeks.

2-[2-(2-Chloroethoxy)Ethoxy]Ethanol

20-abx185012
  • EUR 258.00
  • EUR 509.00
  • 100 g
  • 500 g
  • Shipped within 1-2 weeks.

2-[2-(2-Aminoethoxy)Ethoxy]Ethanol

abx186612-1g 1 g
EUR 300.00
  • Shipped within 1-2 weeks.

2-[2-(2-Azidoethoxy)Ethoxy]Ethanol

20-abx187846
  • EUR 328.00
  • EUR 328.00
  • 1 g
  • 5 g
  • Shipped within 1-2 weeks.

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 805.00
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1132.00
  • Category: Cas9

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 153.00
  • Category: Cas9

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 4941.00
  • Category: PinPoint Integrase Tools

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 4941.00
  • Category: PinPoint Integrase Tools

Glucose Assay Kit

abx090673-1Kit 1 Kit
EUR 237.00
  • Shipped within 5-10 working days.

ADA Assay Kit

abx090675-100tests 100 tests
EUR 237.00
  • Shipped within 5-10 working days.

Glutamate Assay Kit

abx096004-100Assays 100 Assays
EUR 441.00
  • Shipped within 5-10 working days.

Glutathione Assay Kit

abx096005-100Assays 100 Assays
EUR 378.00
  • Shipped within 5-10 working days.

Trehalase Assay Kit

abx096014-100Assays 100 Assays
EUR 551.00
  • Shipped within 5-10 working days.

Pyruvate Assay Kit

abx097982-100Assays 100 Assays
EUR 472.00
  • Shipped within 5-10 working days.

NADPase Assay Kit

abx097983-100Assays 100 Assays
EUR 504.00
  • Shipped within 5-10 working days.

Starch Assay Kit

abx097988-100Assays 100 Assays
EUR 441.00
  • Shipped within 5-10 working days.

Trehalose Assay Kit

abx097995-100Assays 100 Assays
EUR 472.00
  • Shipped within 5-10 working days.

ADA Assay Kit

abx098403-Hitachi7060R190ml2R290ml1 Hitachi 7060; R1: 90ml×2 R2: 90ml×1
EUR 739.00
  • Shipped within 5-12 working days.

ADA Assay Kit

abx098403-Hitachi7170R140ml4R220ml4 Hitachi 7170; R1: 40ml×4 R2: 20ml×4
EUR 801.00
  • Shipped within 5-12 working days.

ADA Assay Kit

abx098403-Hitachi7170R160ml4R260ml2 Hitachi 7170; R1: 60ml×4 R2: 60ml×2
EUR 911.00
  • Shipped within 5-12 working days.

ADA Assay Kit

abx098403-Toshiba40R150ml4R250ml2 Toshiba 40; R1: 50ml×4 R2: 50ml×2
EUR 786.00
  • Shipped within 5-12 working days.

Calcium Assay Kit

abx098414-Hitachi7020R140ml2R240ml2 Hitachi 7020; R1: 40ml×2 R2: 40ml×2
EUR 206.00
  • Shipped within 5-12 working days.

Calcium Assay Kit

abx098414-Hitachi7060R190ml1R290ml1 Hitachi 7060; R1: 90ml×1 R2: 90ml×1
EUR 206.00
  • Shipped within 5-12 working days.

Calcium Assay Kit

abx098414-Toshiba40R140ml2R240ml2 Toshiba 40; R1: 40ml×2 R2: 40ml×2
EUR 206.00
  • Shipped within 5-12 working days.

Calcium Assay Kit

abx098414-UniversalR140ml2R240ml2 Universal; R1: 40ml×2 R2: 40ml×2
EUR 206.00
  • Shipped within 5-12 working days.

Cholinesterase Assay Kit

abx098416-Hitachi7170R120ml1R25ml1 Hitachi 7170; R1: 20ml×1 R2: 5ml×1
EUR 300.00
  • Shipped within 5-12 working days.

Cholinesterase Assay Kit

abx098416-Hitachi7170R140ml3R230ml1 Hitachi 7170; R1: 40ml×3 R2: 30ml×1
EUR 316.00
  • Shipped within 5-12 working days.

Cholinesterase Assay Kit

abx098416-Hitachi7170R160ml2R230ml1 Hitachi 7170; R1: 60ml×2 R2: 30ml×1
EUR 316.00
  • Shipped within 5-12 working days.

Cholinesterase Assay Kit

abx098416-Toshiba40R140ml4R240ml1 Toshiba 40; R1: 40ml×4 R2: 40ml×1
EUR 331.00
  • Shipped within 5-12 working days.

Cholinesterase Assay Kit

abx098416-UniversalR160ml2R215ml2 Universal; R1: 60ml×2 R2: 15ml×2
EUR 316.00
  • Shipped within 5-12 working days.

Creatinine Assay Kit

abx098422-Hitachi7020R150ml3R250ml1 Hitachi 7020; R1: 50ml×3 R2: 50ml×1
EUR 519.00
  • Shipped within 5-12 working days.

Creatinine Assay Kit

abx098422-Hitachi7060R190ml2R260ml1 Hitachi 7060; R1: 90ml×2 R2: 60ml×1
EUR 472.00
  • Shipped within 5-12 working days.

Creatinine Assay Kit

abx098422-Toshiba120R140ml3R240ml1 Toshiba 120; R1: 40ml×3 R2: 40ml×1
EUR 566.00
  • Shipped within 5-12 working days.

Creatinine Assay Kit

abx098422-Toshiba120R150ml3R250ml1 Toshiba 120; R1: 50ml×3 R2: 50ml×1
EUR 519.00
  • Shipped within 5-12 working days.

Creatinine Assay Kit

abx098422-Toshiba40R150ml3R250ml1 Toshiba 40; R1: 50ml×3 R2: 50ml×1
EUR 519.00
  • Shipped within 5-12 working days.

Fructosamine Assay Kit

abx098427-Hitachi7020R140ml2R220ml1 Hitachi 7020; R1: 40ml×2 R2: 20ml×1
EUR 253.00
  • Shipped within 5-12 working days.

Fructosamine Assay Kit

abx098427-Hitachi7060R190ml2R245ml1 Hitachi 7060; R1: 90ml×2 R2: 45ml×1
EUR 253.00
  • Shipped within 5-12 working days.

Fructosamine Assay Kit

abx098427-Hitachi7170R120ml1R25ml1 Hitachi 7170; R1: 20ml×1 R2: 5ml×1
EUR 206.00
  • Shipped within 5-12 working days.